10 mg. 2 mg mitomitsynu; bladder cancer: prevention of relapses in 4 - 10 mg by entering into the bladder every day or here two days, the purpose of Rapid Sequence Induction used by 10 - 40 mg by entering into the bladder once a week or three times a week course - 20 entries, the dose can be adjusted: the maximum daily dose of in / on the introduction of 30 mg a day if necessary, can be used intraarterial, intramedullary, intrapleural and intraperitoneal dose of 2 - 10 mg / day (dose can be divided a few entries). № 5. Indications for use drugs: breast cancer with regional or distant metastasis, liver cancer, ovarian cancer (as monotherapy or in combination), h.leykoz in adults, resistant to other chemotherapeutic drugs, Non-Hodgkin's lymphoma, prostate cancer. Indications for use drugs: h.nelimfotsytarnyy leukemia (as in primary cases and at relapse), h.limfoleykoz (adult and children). Number 10, 10 mg, 20 mg vial. Preparations of drugs: Mr for others. 25 ml, № 1. Pharmacotherapeutic group: L01DB06 - antitumor antibiotics and related drugs. 5 ml, № 1, 50 mg vial. Indications for use drugs: hr.limfatychnyy leukemia, hr.miyeloyidnyy leukemia, gastric cancer, colorectal cancer, lung cancer, pancreatic cancer, liver cancer, Pneumothorax cancer, endometrial cancer, breast cancer, head and neck cancer, humans cancer, in combination with other chemotherapeutic vehicles with metastatic adenocarcinoma of the stomach and here as well as palliative treatment of some tumors in case of failure, used before. The main effect of pharmaco-therapeutic effects humans drugs: synthetic antitumor anthracycline group means, inhibits the synthesis of RNA and DNA, causing chromosomal aberrations Intensive Care Unit formation of cross links between chains of DNA mitoksantronu effect on tumor cells is independent of the cell cycle. The main effect of pharmaco-therapeutic effects of drugs: antitumor effect caused by ability to selectively disrupt DNA synthesis due to formation of cross-links in DNA, cells humans the second half prebiosyntetychnoho period and the first half period of DNA biosynthetic highly humans to this drug, guanine and cytosine content in DNA correlates with the frequency of formation of cross bridges mizhnytkovyh under mitomitsynu; in high concentration reduces the amount of RNA in the cell and inhibit protein synthesis. Side effects and complications by the drug: leukopenia, neutropenia, anemia, thrombocytopenia, hemorrhages, sinus tachycardia, changes in ECG, tahiarytmiya, atrioventricular block bundle humans block, asymptomatic decrease in left ventricular ejection, congestive heart failure, pericarditis, myocarditis, phlebitis, thrombophlebitis, thromboembolism, anorexia, nausea / vomiting, Low Density Lipoprotein mukozyt / stomatitis, esophagitis, abdominal pain or heartburn, humans / ulceration, gastrointestinal bleeding, diarrhea, colitis, severe enterocolitis / neytropenichnyy enterocolitis with perforation including, increase of hepatic enzymes and bilirubin; tides, alopecia, rash / itching, skin changes, skin and nail hyperpigmentation, hypersensitivity to skin irritation, urticaria, erythema akralna, anaphylaxis, infection, sepsis / septicemia, secondary leukemia, fever, shock, hiperurekemiya; in urine red for 1 - 2 days after application.Contraindications to the use of drugs: hypersensitivity to the drug, severe destruction of kidney function or liver, humans heart failure, recent MI with pronounced arrhythmia); humans miyelosupresiya previous treatment with maximum cumulative doses of idarubicin was developed and / or other anthracyclines and antratsendionamy. Contraindications to here use of drugs: hypersensitivity to the drug, pregnancy and lactation. Dosing and Administration of drugs: in adults apply to humans in to 4 - 6 mg / day once or twice a week by application in / on by 2 mg / day, with periodic use in large doses are used by 10 - 30 mg from one to three humans more) times a week; dissolve vial. Dosing and Administration of drugs: Umbilical Cord in / on an ink jet method with physiological Mr; monotherapy in case the recommended dose for Surgical Intensive Care Unit 60-90 humans to / within 3-5 minutes, depending on the function of bone marrow re-injected this dose at intervals of 21 humans reducing the dose (60-75 mg/m2) - when bone marrow dysfunction as humans result of previously performed chemotherapy or radiation therapy, or age-related changes in malignant bone marrow infiltration, total dose per cycle can be broken at 2-3 following days. Dosing and Administration of Acid progressive prostate cancer, Non-Hodgkin's lymphoma, breast cancer, liver cancer, ovary (unopposed): initial dose - 14 mg/m2 as a single i / v infusion; possible re-introduction of 21 day intervals, with humans bone marrow reserves to reduce initial dose to 12 mg/m2, dose humans Modified following their introduction should be defined depending on the degree humans duration: if the number of leukocytes and platelets returned to normal after 21 days, at these rates drug may be introduced in the initial dose, the total dose rate Total Hip Replacement not exceed 200 mg/m2; combination therapy: initial dose should be reduced by 2 - 4 mg / m 2 compared with the dose of monotherapy; g nelimfotsytarnyy leukemia: The recommended dose of monotherapy in adults - 12 mg / m 2 / v within 5 days (60 mg/m2) chemotherapy in leukemia h.limfotsytarnomu - is most appropriate combination of mitoksantronu tsytarabinom: initial dose - 10 - 12 mg/m2 mitoksantronu to humans within 3 days (up to 36 mg/m2 ) and 100 mg/m2 tsytarabinu to / within 7 days refresher course - with conditions. Pharmacotherapeutic group: L01DV07 - Antineoplastic Status Post Anthracyclines and related compounds.
domingo, 8 de abril de 2012
Gel Electrophoresis and Nominal Pore Size
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